- Catalogue N°
- 862.001.001 - 1 x 96 Discovery (plate not included)
862.001.001P - 1 x 96 Discovery (non-sterile plate)
862.001.001S - 1 x 96 Discovery (sterile plate)
862.001.005 - 5 x 96 (plates not included)
862.001.005P - 5 x 96 (non-sterile plates)
862.001.005S - 5 x 96 (sterile plates)
862.001.010 - 10 x 96 (plates not included)
862.001.010P - 10 x 96 (non-sterile plates)
862.001.010S - 10 x 96 (sterile plates)
862.001.015 - 15 x 96 (plates not included)
862.001.015P - 15 x 96 (non-sterile plates)
862.001.015S - 15 x 96 (sterile plates)
862.001.020 - 20 x 96 (plates not included)
862.001.020P - 20 x 96 (non-sterile plates)
862.001.020S - 20 x 96 (sterile plates)
- Target species
- Recognizes natural murine IL-2
- 3h after cell stimulation
- Cross Reaction
- No cross reactivity with other murine cytokines
- Kit Content
- Diaclone ELISpot Sets include capture and detection antibodies, Streptavidin - Alkaline Phosphatase conjugated, BSA, BCIP/NTB and blocking reagent.
- Additional Information
- Spots read visually or with reader
IL-2 is a powerful immunoregulatory lymphokine produced by T-Cells in response to antigenic or mitogenic activation. IL-2 stimulates growth and differentiation of B-Cells, most T-cells, NK cells, monocytes and macrophages.
Mature IL-2 is a 15.4kDa globular glycoprotein containing 133 amino acid residues including one intrachain disulfide bond between residues 58 and 105.
Apart from its most important role to mediate antigen-specific T-lymphocyte proliferation, IL-2 modulates the expression of interferon-g and major histocompatibility antigens.
Alterations in the ability of T-cell to synthesize IL-2 have been observed in physiologic and pathologic states. Currently, IL-2 is used to enhance the immune system of patients for the treatment of cancer and infectious disease.
Version 8 - 07.19
For research use only
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