Human IL-2 ELISpot Set
Product Specifications
- Catalogue N°
- 856.001.001 - 1 x 96 Discovery (plate not included)
856.001.001P - 1 x 96 Discovery (non-sterile plate)
856.001.001S - 1 x 96 Discovery (sterile plate)
856.001.005 - 5 x 96 (plates not included)
856.001.005P - 5 x 96 (non-sterile plates)
856.001.005S - 5 x 96 (sterile plates)
856.001.010 - 10 x 96 (plates not included)
856.001.010P - 10 x 96 (non-sterile plates)
856.001.010S - 10 x 96 (sterile plates)
856.001.015 - 15 x 96 (plates not included)
856.001.015P - 15 x 96 (non-sterile plates)
856.001.015S - 15 x 96 (sterile plates)
856.001.020 - 20 x 96 (plates not included)
856.001.020P - 20 x 96 (non-sterile plates)
856.001.020S - 20 x 96 (sterile plates) - Target species
- Human
- Specificity
- Recognizes natural human IL-2
- Incubation
- 3h after cell stimulation
- Cross Reaction
- No cross reactivity with other human cytokines. Cross reactivity with simian IL-2.
- Kit Content
- Diaclone ELISpot Sets include capture and detection antibodies, Streptavidin - Alkaline Phosphatase conjugated, BSA, BCIP/NTB and blocking reagent.
- Additional Information
- Spots read visually or with reader
References
- Dosset, M. et al., Clin Cancer Res., 2012; 18(22): 6284-95 - Pubmed link
- Kalogerakou, F. et al.,Hippokratia,2008; 12(4): 230-5. - Pubmed link
- Montcuquet, N. et al., Immunology,2008;125(3): 320-30. - Pubmed link
- Rinaldi, M. et al.,Thorax, 2012; 10.1136/thoraxjnl-2011-200690 - Pubmed link
- Van Gulck, E. R. et al, J. Virol,2008; 82(7): 3561-3573. - Pubmed link
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- 950.010.048 - Human IL-2 ELISA Kit
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- 861.000.001 - Murine IL-2 ELISA Set
- 856.001.001PC - Human IL-2 ELISpot Kit
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- 874.042.001 - Human IFN-γ / IL-2 Dual Fluorospot Set
- 874.050.001 - Human IL-10 / IL-2 Dual ELISpot Set
- 862.001.001 - Murine IL-2 ELISpot Set
- 862.001.001PC - Murine IL-2 ELISpot Kit
- 869.000.010 - Human IL-2 ELISpot Pair
- 870.010.010 - Murine IL-2 ELISpot Pair
- 874.052.001 - Human IL-10 / IL-2 Dual Fluorospot Set
- 670.100.096 - Rat IL-2 ELISA kit
- 715-H02-010-CF - Recombinant Human Interleukin-2 (IL-2)-CF
- 715-H02-010-BSA - Recombinant Human Interleukin-2 (IL-2)-BSA
BACKGROUND
IL-2 is a powerful immunoregulatory lymphokine produced by T-Cells in response to antigenic or mitogenic activation. IL-2 stimulates growth and differentiation of B-Cells, most T-cells, NK cells, monocytes and macrophages.
Mature IL-2 is a 15.4kDa globular glycoprotein containing 133 amino acid residues including one intrachain disulfide bond between residues 58 and 105.
Apart from its most important role to mediate antigen-specific T-lymphocyte proliferation, IL-2 modulates the expression of interferon-g and major histocompatibility antigens.
Alterations in the ability of T-cell to synthesize IL-2 have been observed in physiologic and pathologic states. Currently, IL-2 is used to enhance the immune system of patients for the treatment of cancer and infectious disease.
Version 11 - 02.18
For research use only
For any order, the purchaser acknowledges having read and accepted the terms and conditions described on the Diaclone website.