- Catalogue N°
- 869.160.010 - 10 x 96 tests
- Target species
- Recognizes natural human IL-17F
- Cross Reaction
- No cross reactivity with other human cytokines
- Kit Content
- Diaclone ELISpot matched antibody pairs are extensively validated and include pre-titrated capture antibody and biotinylated detection antibody. Antibodies are supplied in quantities sufficient for 10 x 96 samples.
IL-17F, discovered in 2001, is a member of the IL-17 family of cytokines produced by activated T-cells CD4+ and monocytes. IL-17F has been considered as an inflammatory cytokine since it induces many proinflammatory cytokines and chemokines. IL-17F shares strongest homology to IL-17A (sharing about 50% amino acid). The IL-17A and IL-17F genes are localized in the same chromosome region. An IL-17A/F heterodimer biologically active was found to be expressed in Th17 cells together with IL-17A and IL-17F homodimers.
Version 3 - 02.18
For research use only
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