Human IL-17A ELISpot Set

Product Specifications

Catalogue N°

856.151.001 - 1 x 96 Discovery (plate not included)
856.151.001P - 1 x 96 Discovery (non-sterile plate)
856.151.001S - 1 x 96 Discovery (sterile plate)
856.151.005 - 5 x 96 (plates not included)
856.151.005P - 5 x 96 (non-sterile plates)
856.151.005S - 5 x 96 (sterile plates)
856.151.010 - 10 x 96 (plates not included)
856.151.010P - 10 x 96 (non-sterile plates)
856.151.010S - 10 x 96 (sterile plates)
856.151.015 - 15 x 96 (plates not included)
856.151.015P - 15 x 96 (non-sterile plates)
856.151.015S - 15 x 96 (sterile plates)
856.151.020 - 20 x 96 (plates not included)
856.151.020P - 20 x 96 (non-sterile plates)
856.151.020S - 20 x 96 (sterile plates)

Target species

Human

Specificity

Recognizes natural human IL-17A

Incubation

3h after cell stimulation

Cross Reaction

No cross reactivity with other human cytokines

Kit Content

Diaclone ELISpot Sets include capture and detection antibodies, Streptavidin - Alkaline Phosphatase conjugated, BSA, BCIP/NTB and blocking reagent.

Additional Information

Spots read visually or with reader

• References
• Related products

BACKGROUND

Interleukin-17 (IL-17, or IL-17A) is the founding member of a group of cytokines called the IL-17 family. IL-17A was originally identified as a transcript from a rodent T-cell hybridoma by Rouvier et al. in 1993. IL-17A is involved in inducing and mediating proinflammatory responses, commonly associated with allergic responses and induces the production of many other cytokines (such as IL-6, G-CSF, GM-CSF, IL-1β, TGF-β, TNFα), chemokines (including IL-8, GRO-α and MCP-1) and prostaglandins (e.g. PGE2) from many cell types (fibroblasts, endothelial cells, epithelial cells, keratinocytes and macrophages). IL-17A function is also essential to a subset of CD4+ T-Cells called T helper 17 (Th17) cells.

Version 6 - 07.19

For research use only

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