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Human IL-17A ELISpot Set

Product Specifications

Catalogue N°
856.151.001 - 1 x 96 Discovery (plate not included)
856.151.001P - 1 x 96 Discovery (non-sterile plate)
856.151.001S - 1 x 96 Discovery (sterile plate)
856.151.005 - 5 x 96 (plates not included)
856.151.005P - 5 x 96 (non-sterile plates)
856.151.005S - 5 x 96 (sterile plates)
856.151.010 - 10 x 96 (plates not included)
856.151.010P - 10 x 96 (non-sterile plates)
856.151.010S - 10 x 96 (sterile plates)
856.151.015 - 15 x 96 (plates not included)
856.151.015P - 15 x 96 (non-sterile plates)
856.151.015S - 15 x 96 (sterile plates)
856.151.020 - 20 x 96 (plates not included)
856.151.020P - 20 x 96 (non-sterile plates)
856.151.020S - 20 x 96 (sterile plates)
Target species
Human
Specificity
Recognizes natural human IL-17A
Incubation
3h after cell stimulation
Cross Reaction
No cross reactivity with other human cytokines
Kit Content
Diaclone ELISpot Sets include capture and detection antibodies, Streptavidin - Alkaline Phosphatase conjugated, BSA, BCIP/NTB and blocking reagent.
Additional Information
Spots read visually or with reader

BACKGROUND

Interleukin-17 (IL-17, or IL-17A) is the founding member of a group of cytokines called the IL-17 family. IL-17A was originally identified as a transcript from a rodent T-cell hybridoma by Rouvier et al. in 1993. IL-17A is involved in inducing and mediating proinflammatory responses, commonly associated with allergic responses and induces the production of many other cytokines (such as IL-6, G-CSF, GM-CSF, IL-1β, TGF-β, TNFα), chemokines (including IL-8, GRO-α and MCP-1) and prostaglandins (e.g. PGE2) from many cell types (fibroblasts, endothelial cells, epithelial cells, keratinocytes and macrophages). IL-17A function is also essential to a subset of CD4+ T-Cells called T helper 17 (Th17) cells.

Version 6 - 07.19

For research use only

Documents

For any order, the purchaser acknowledges having read and accepted the terms and conditions described on the Diaclone website.

Formats Available

856.151.001 1 x 96 Discovery (plate not included)
856.151.001P 1 x 96 Discovery (non-sterile plate)
856.151.001S 1 x 96 Discovery (sterile plate)
856.151.005 5 x 96 (plates not included)
856.151.005P 5 x 96 (non-sterile plates)
856.151.005S 5 x 96 (sterile plates)
856.151.010 10 x 96 (plates not included)
856.151.010P 10 x 96 (non-sterile plates)
856.151.010S 10 x 96 (sterile plates)
856.151.015 15 x 96 (plates not included)
856.151.015P 15 x 96 (non-sterile plates)
856.151.015S 15 x 96 (sterile plates)
856.151.020 20 x 96 (plates not included)
856.151.020P 20 x 96 (non-sterile plates)
856.151.020S 20 x 96 (sterile plates)

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