Human IL-17A ELISpot Pair

Product Specifications

Catalogue N°

869.150.010 - 10 x 96 tests

Target species

Human

Specificity

Recognizes natural human IL-17A

Cross Reaction

No cross reactivity with other human cytokines

Kit Content

Diaclone ELISpot matched antibody pairs are extensively validated and include pre-titrated capture antibody and biotinylated detection antibody. Antibodies are supplied in quantities sufficient for 10 x 96 samples.

• Related products

BACKGROUND

Interleukin-17 (IL-17, or IL-17A) is the founding member of a group of cytokines called the IL-17 family. IL-17A was originally identified as a transcript from a rodent T-cell hybridoma by Rouvier et al. in 1993. IL-17A is involved in inducing and mediating proinflammatory responses, commonly associated with allergic responses and induces the production of many other cytokines (such as IL-6, G-CSF, GM-CSF, IL-1β, TGF-β, TNFα), chemokines (including IL-8, GRO-α and MCP-1) and prostaglandins (e.g. PGE2) from many cell types (fibroblasts, endothelial cells, epithelial cells, keratinocytes and macrophages). IL-17A function is also essential to a subset of CD4+ T-Cells called T helper 17 (Th17) cells.

Version 3 - 02.18

For research use only

Documents

• Human IL-17A ELISpot Pair insert
• Safety Data Sheet ELISpot Pairs

For any order, the purchaser acknowledges having read and accepted the terms and conditions described on the Diaclone website.