- Catalogue N°
- 860.070.048 - 1 x 48 Discovery (pre-coated)
860.070.096 - 1 x 96 (pre-coated)
860.070.192 - 2 x 96 (pre-coated)
- Assay Range
- 15.6 pg/ml - 500 pg/ml
- Target species
- Recognizes both natural and recombinant murine IL-17A
- Sample Type
- Cell culture supernatant and serum tested, other body fluids suitable
- Sample Size
- 50 µl
- Kit Content
- Diaclone ELISA Kits include pre-coated strip plates, biotinylated secondary antibody, standards, controls (where applicable), buffers, streptavidin-HRP, TMB, stop reagents and a detailed procedure.
Interleukin-17 (IL-17, or IL-17A) is the founding member of a group of cytokines called the IL-17 family. IL-17A, was originally identified as a transcript from a rodent T-cell hybridoma by Rouvier et al. in 1993.
IL-17A is involved in inducing and mediating proinflammatory responses, commonly associated with allergic responses and induces the production of many other cytokines (such as IL-6, G-CSF, GM-CSF, IL-1β, TGF-β, TNF-α), chemokines (including IL-8, GRO-α and MCP-1) and prostaglandins (e.g. PGE2) from many cell types (fibroblasts, endothelial cells, epithelial cells, keratinocytes and macrophages).
IL-17A function is also essential to a subset of CD4+ T-Cells called T helper 17 (Th17) cells.
Version 3 - 07.19
For research use only
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