Search for products

Anti-Human IL-17A Unconjugated

Product Specifications

Catalogue N°
853.943.020 - 200 tests / 2ml
Target species
Human
Specificity
Recognizes both natural and recombinant IL-17A
Clone
B-A50
Application
Flow Cytometry
Hybridoma
Myeloma X63/AG.8653 x Balb/c node cells
Immunisation
Recombinant human IL-17A
Quantity
200 Tests / 2ml (Discovery Size also available please enquire)
Isotype
Mouse IgG2b Kappa light chain
Format
Phosphate-buffered saline with 1 % BSA and 0.09 % sodium azide
Storage
Stable at +2-8°C for 12 months. For longer storage freeze aliquots.
Working Dilution
Use 10 μl to label 0,5.106 cells or 50 μl of whole blood
Anti-Human IL-17A Unconjugated
A typical staining pattern with B-A50 monoclonal antibody of TH17 cells, activated on the left and non-activated (negative control) on the right

Sodium azide is a poisonous and hazardous substance, handle and dispose of properly


BACKGROUND

Interleukin-17 (IL-17, or IL-17A) is the founding member of a group of cytokines called the IL-17 family. IL-17A, was originally identified as a transcript from a rodent T-cell hybridoma by Rouvier et al. in 1993.

IL-17A is involved in inducing and mediating proinflammatory responses, commonly associated with allergic responses and induces the production of many other cytokines (such as IL-6, G-CSF, GM-CSF, IL-1β, TGF-β, TNF-α), chemokines (including IL-8, GRO-α and MCP-1) and prostaglandins (e.g. PGE2) from many cell types (fibroblasts, endothelial cells, epithelial cells, keratinocytes and macrophages).

IL-17A function is also essential to a subset of CD4+ T-Cells called T helper 17 (Th17) cells.

Version 7 - 06.19

For research use only

Documents

For any order, the purchaser acknowledges having read and accepted the terms and conditions described on the Diaclone website.

Formats Available

853.943.020 200 tests / 2ml

Ordering options

Place an order
by phone: +33 (0)3 81 41 38 38
or by email:

Please contact us to discuss bulk orders