- Catalogue N°
- 856.171.001PC - 1 x 96 Discovery (pre-coated plate)
856.171.005PC - 5 x 96 (pre-coated plates)
- Target species
- Recognizes natural human IL-17A/F
- 3h after cell stimulation
- Kit Content
- Diaclone Pre-coated ELISpot kits include precoated PVDF plates, Detection antibody, Alkaline phosphatase conjugate, BSA, BCIP/NBT ready-to-use substrate buffer.
IL-17A and IL-17F are members of the IL-17 family that play crucial roles in allergic inflammation. They share the strongest homology and the two genes are located on the same chromosome region. Recent studies have shown that activated human CD4+T cells, termed Th17 cells, not only express IL-17A and IL-17F homodimers, but also an IL-17A/F heterodimer cytokine. IL-17A/F is a biologically active protein that induces chemokine production and airway neutrophilia with intermediate potency between IL-17A (most potent) and IL-17F (least potent).
Version 4 - 07.19
For research use only
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