Human IL-17A/F ELISpot Pair

Product Specifications

Catalogue N°

869.170.010 - 10 x 96 tests

Target species

Human

Specificity

Recognizes natural human IL-17A/F

Cross Reaction

No cross reactivity with other human cytokines

Kit Content

Diaclone ELISpot matched antibody pairs are extensively validated and include pre-titrated capture antibody and biotinylated detection antibody. Antibodies are supplied in quantities sufficient for 10 x 96 samples.

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BACKGROUND

IL-17A and IL-17F are members of the IL-17 family that play crucial roles in allergic inflammation. They share the strongest homology and the two genes are located on the same chromosome region. Recent studies have shown that activated human CD4+T cells, termed Th17 cells, not only express IL-17A and IL-17F homodimers, but also an IL-17A/F heterodimer cytokine. IL-17A/F is a biologically active protein that induces chemokine production and airway neutrophilia with intermediate potency between IL-17A (most potent) and IL-17F (least potent).

Version 4 - 07.19

For research use only

Documents

• Human IL-17AF ELISpot Pair insert
• Safety Data Sheet ELISpot Pairs

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