Human IL-17A/F ELISpot Set
Product Specifications
- Catalogue N°
- 856.171.001 - 1 x 96 Discovery (plate not included)
856.171.001P - 1 x 96 Discovery (non-sterile plate)
856.171.001S - 1 x 96 Discovery (sterile plate)
856.171.005 - 5 x 96 (plates not included)
856.171.005P - 5 x 96 (non-sterile plates)
856.171.005S - 5 x 96 (sterile plates)
856.171.010 - 10 x 96 (plates not included)
856.171.010P - 10 x 96 (non-sterile plates)
856.171.010S - 10 x 96 (sterile plates)
856.171.015 - 15 x 96 (plates not included)
856.171.015P - 15 x 96 (non-sterile plates)
856.171.015S - 15 x 96 (sterile plates)
856.171.020 - 20 x 96 (plates not included)
856.171.020P - 20 x 96 (non-sterile plates)
856.171.020S - 20 x 96 (sterile plates) - Target species
- Human
- Specificity
- Recognizes natural human IL-17A/F
- Incubation
- 3h after cell stimulation
- Cross Reaction
- No cross reactivity with other human cytokines
- Kit Content
- Diaclone ELISpot Sets include capture and detection antibodies, Streptavidin - Alkaline Phosphatase conjugated, BSA, BCIP/NTB and blocking reagent.
- Additional Information
- Spots read visually or with reader
BACKGROUND
IL-17A and IL-17F are members of the IL-17 family that play crucial roles in allergic inflammation. They share the strongest homology and the two genes are located on the same chromosome region. Recent studies have shown that activated human CD4+T cells, termed Th17 cells, not only express IL-17A and IL-17F homodimers, but also an IL-17A/F heterodimer cytokine. IL-17A/F is a biologically active protein that induces chemokine production and airway neutrophilia with intermediate potency between IL-17A (most potent) and IL-17F (least potent).
Version 5 - 07.19
For research use only
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