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Human CD263 ELISA Kit

Product Specifications

Catalogue N°
850.840.048 - 1 x 48 Discovery (pre-coated)
850.840.096 - 1 x 96 (pre-coated)
850.840.192 - 2 x 96 (pre-coated)
Assay Range
312.5 pg/ml - 10000 pg/ml
Sensitivity
147 pg/ml
Target species
Human
Specificity
Specific for human TRAIL R3 / DcR1
Incubation
3h40
Sample Type
Serum, Cell lysates
Sample Size
100 µl
Cross Reaction
No cross reactivity was observed with TRAIL, CD117, IL-6R, IL-2R, CD116, TRAIL R1, TRAIL R2, TRAIL R4, CD178, and Granzyme B.
Kit Content
Diaclone ELISA Kits include pre-coated strip plates, biotinylated secondary antibody, standards, controls (where applicable), buffers, streptavidin-HRP, TMB, stop reagents and a detailed procedure.
Synonym
DcR1
TRAIL R3
CD263 ELISA Kit
CD263 ELISA Kit


BACKGROUND

Human Trail R3, also called DcR1, CD263, LIT, or TRID is a glycosyl-phosphatidylinositol-linked membrane protein which binds TRAIL with high affinity. In the Trail receptor family, Trail R3 (DcR1) but also Trail R4 (DcR2) antagonize TRAIL-induced apoptosis whereas Trail R1 (DR4) and Trail R2 (DR5) transduce an apoptosis signal. Trail R3 has extracellular TRAIL-binding cystein-rich domain but lacks intracellular signalling domain. Expression of Trail R3 has been shown to protect cells bearing Trail R1 and/or Trail R2 from Trail-induced apoptosis. Many tumor cell lines don’t express the decoy receptors and are therefore sensitive to TRAIL if they express Trail R1 and/or Trail R2.

Version 5 - 07.19

For research use only

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For any order, the purchaser acknowledges having read and accepted the terms and conditions described on the Diaclone website.

Formats Available

850.840.048 1 x 48 Discovery (pre-coated)
850.840.096 1 x 96 (pre-coated)
850.840.192 2 x 96 (pre-coated)

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