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Human CD264 ELISA Kit

Product Specifications

Catalogue N°
850.850.048 - 1 x 48 Discovery (pre-coated)
850.850.096 - 1 x 96 (pre-coated)
850.850.192 - 2 x 96 (pre-coated)
Assay Range
312.5 pg/ml - 10000 pg/ml
Sensitivity
64 pg/ml
Target species
Human
Specificity
Specific for human TRAIL R4 / DcR2 / TRUNDD
Incubation
3h40
Sample Type
Serum, Cell lysates
Sample Size
100 µl
Cross Reaction
No cross reactivity was observed with TRAIL, CD117, Il-6R, IL-2R, CD116, TRAIL R1, TRAIL R2, TRAIL R3, CD178 and Granzyme B.
Kit Content
Diaclone ELISA Kits include pre-coated strip plates, biotinylated secondary antibody, standards, controls (where applicable), buffers, streptavidin-HRP, TMB, stop reagents and a detailed procedure.
Synonym
DcR2
TRAIL R4
CD264 ELISA Kit
CD264 ELISA Kit

BACKGROUND

Human Trail R4, also called DcR2, CD264 or TRUNND is a type 1 TNF R family membrane protein which is a receptor for TRAIL. In the Trail receptor family, Trail R4 (DcR2) but also Trail R3 (DcR1) antagonize TRAIL-induced apoptosis whereas Trail R1 (DR4) and Trail R2 (DR5) transducer an apoptosis signal. Trail R4 has a truncated intracellular domain.  Overexpression of Trail R4 has been shown to protect cells bearing Trail R1 and/or Trail R2 from Trail-induced apoptosis. Many tumor cell lines don’t express the decoy receptors and are therefore sensitive to TRAIL if they express Trail R1 and/or Trail R2.

Version 6 - 04.20

For research use only

Documents

For any order, the purchaser acknowledges having read and accepted the terms and conditions described on the Diaclone website.

Formats Available

850.850.048 1 x 48 Discovery (pre-coated)
850.850.096 1 x 96 (pre-coated)
850.850.192 2 x 96 (pre-coated)

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