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Human IP-10 ELISA set

Product Specifications

Catalogue N°
851.870.001 - 1 x 96 Discovery
851.870.005 - 5 x 96
851.870.010 - 10 x 96
851.870.015 - 15 x 96
851.870.020 - 20 x 96
Assay Range
6.25 pg/ml - 200 pg/ml
Sensitivity
5.7 pg/ml (determined with Diaclone IP-10 ELISA Kit)
Target species
Human
Specificity
Recognizes both natural and recombinant form of the molecule
Incubation
From sample to end 3h45
Sample Type
Serum, Plasma, Cell culture supernatant, buffered solutions
Sample Size
100 µl
Cross Reaction
No cross reactivity with other human molecules
Kit Content
Diaclone ELISA Sets include capture and biotinylated detection antibody, one standard per plate, Streptavidin-HRP, TMB, and detailed procedure including buffer composition.
Synonym
CXCL10

BACKGROUND

IP-10 (Interferon-gamma inducible Protein 10kDa) also known as CXCL10, is secreted by several cell types in response to IFNg and LPS. These cell types include monocytes, endothelial cells and fibroblasts.The gene for IP-10 is located on chromosome 4 in a cluster among several other cytokines and encodes a 98 amino acid precursor protein.

Several roles have been attributed to IP-10, such as chemoattraction for monocytes and T cells (but not for neutrophils), inhibition of bone marrow colony formation and angiogenesis, promotion of T cells adhesion molecule expression.

IP-10 shares a common receptor, CXCR3, with the chemokine MIG, but has been shown to play a distinct role in host defense in infections.

IP-10 expression has been associated with HIV infection, is involved in inflammatory skin disease and other allergic diseases; it appears in inflammation of the nervous system and in Alzheimer’s disease (astrocytes expressing IP-10 are commonly associated with senile plaques).

Version 6 - 07.19

For research use only

Documents

For any order, the purchaser acknowledges having read and accepted the terms and conditions described on the Diaclone website.

Formats Available

851.870.001 1 x 96 Discovery
851.870.005 5 x 96
851.870.010 10 x 96
851.870.015 15 x 96
851.870.020 20 x 96

Ordering options

Place an order
by phone: +33 (0)3 81 41 38 38
or by email: info [at] diaclone [dot] com ( Subject: Diaclone's order, Body: Human IP-10 ELISA set 851.870.001 - 1 x 96 Discovery 851.870.005 - 5 x 96 851.870.010 - 10 x 96 851.870.015 - 15 x 96 851.870.020 - 20 x 96 )

Please contact us to discuss bulk orders