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Human CD62P ELISA kit

Product Specifications

Catalogue N°
850.930.048 - 1 x 48 Discovery (pre-coated)
850.930.096 - 1 x 96 (pre-coated)
850.930.192 - 2 x 96 (pre-coated)
Assay Range
4.4 ng/ml - 140 ng/ml
Sensitivity
3.6 ng/ml
Target species
Human
Specificity
Recognizes both natural and recombinant human P-Selectin
Incubation
2h45
Sample Type
Serum, Plasma, Cell culture supernatant, Amniotic fluid
Sample Size
100 µl
Kit Content
Diaclone ELISA Kits include pre-coated strip plates, biotinylated secondary antibody, standards, controls (where applicable), buffers, streptavidin-HRP, TMB, stop reagents and a detailed procedure.
Synonym
P-Selectin
CD62P ELISA Kit
CD62P ELISA Kit

BACKGROUND

P-selectin (CD62P, LECAM-3) was originally purified from platelets and later found to be expressed also in endothelial cells. In both cell types, P-selectin is constitutively expressed and stored in secretory granules – α-granules in platelets and Weibel-Palade bodies in endothelial cells.

A soluble form of P-selectin, which might represent a proteolytic fragment or a soluble splice variant lacking the transmembrane domain, is found in serum and plasma. High expression of P-selectin or sP-selectin has been implicated in several inflammatory disorders, including adult respiratory distress syndrome, acute lung injury, ischemia-reperfusion injury, Gram-negative septic shock, thrombotic diseases, malaria, systemic sclerosis, connective tissue disease and rheumatoid arthritis. Furthermore, lung injury scores correlate significantly with sP-selectin in plasma of patients with acute lung injury.

Version 14 - 02.20

For research use only

Documents

For any order, the purchaser acknowledges having read and accepted the terms and conditions described on the Diaclone website.

Formats Available

850.930.048 1 x 48 Discovery (pre-coated)
850.930.096 1 x 96 (pre-coated)
850.930.192 2 x 96 (pre-coated)

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