Human CD106 ELISA kit
Product Specifications
- Catalogue N°
- 850.580.048 - 1 x 48 Discovery (pre-coated)
850.580.096 - 1 x 96 (pre-coated)
850.580.192 - 2 x 96 (pre-coated) - Assay Range
- 1.56 ng/ml - 50 ng/ml
- Sensitivity
- 0.6 ng/ml
- Target species
- Human
- Specificity
- Recognizes both natural and recombinant human soluble VCAM-1
- Incubation
- 1h45
- Sample Type
- Serum, Plasma, Cell culture supernatant
- Sample Size
- 100 µl
- Cross Reaction
- No cross reactivity with other human adhesion molecules
- Kit Content
- Diaclone ELISA Kits include pre-coated strip plates, biotinylated secondary antibody, standards, controls (where applicable), buffers, streptavidin-HRP, TMB, stop reagents and a detailed procedure.
- Synonym
- VCAM-1
References
- Atteritano, M. et al., J Clin Endocrinol Metab.,2007;92: 3068 - 3075 - Pubmed link
- Castilla, P. et al., Am J Clin Nutr.,2006;84(1): 252-62. - Pubmed link
- Castilla, P. et al., Am. J. Clinical Nutrition,2008; 87(4): 1053-1061. - Pubmed link
- Chachaj, A. et al.,PLoS One, 2018 May 22;13(5):e0197148. - Pubmed link
- Chen M-C. et al., Chest, 2004; 125(4): 1213 - 1217 - Pubmed link
- Connolly, G. M. et al., BMC Nephrol.,2011; 12: 23. - Pubmed link
- Cosentino, F. et al., Stroke,2009; 40(1): 306-308. - Pubmed link
- Diamanti-Kandarakis, E. et al., Hum Reprod., 2006; 21(6): 1426-31. - Pubmed link
- Ehlermann, P. et al.,Cardiovasc Diabetol.,2006; 5: 6 - Pubmed link
- Engelen, L., et al., Eur. J. Endocrinol.,2011; 164(3): 371-379 - Pubmed link
- Foussat A. et al., Blood, 2001; 98(6): 1678 - 1686 - Pubmed link
- Galea, P. et al., Res Immunol., 1997; 148(2): 109-17. - Pubmed link
- Grooteman, M. P. et al., Nephrol Dial Transplant, 2005; 20(12): 2751-8. - Pubmed link
- Hartweg, J. et al., Clin. Chem.,2007; 53(10): 1858-1860. - Pubmed link
- Hettema, M. E. et al., Arthritis Res Ther.,2008; 10(2): R49 - Pubmed link
- Hidalgo, M. et al.,Genes Nutr.,2012;7(2):295-306 - Pubmed link
- Ho, C. Y. et al., Rheumatology(Oxford),2003; 42(1): 117-22. - Pubmed link
- Janowska, J. et al., Int J Med Sci.,2016;13(7): 490-9. - Pubmed link
- Jha, H. C. et al., Mediators Inflamm., 2009: 561532 - Pubmed link
- Jie, K. E. et al.,Nephrol. Dial. Transplant.,2010; 25(6): 1875-1882. - Pubmed link
- Just, N. et al., Clin Exp Immunol.,2003; 132(1): 61-9. - Pubmed link
- Kunutsor, S.K. et al.,J Atheroscler Thromb., 2017; Aug 1;24(8):804-818 - Pubmed link
- Larsson, S. et al., Int J Chron Obstruct Pulmon Dis.,2011;6: 83-8 - Pubmed link
- le Poole, C. Y. et al.,Perit. Dial. Int.,2013;33(2): 208-212 - Pubmed link
- Liao, B. et al., Emerg Microbes Infect.,2015;4(4):e24 - Pubmed link
- Lieuw-A-Fa,M.L. et al., Nephrol. Dial. Transplant., 2004; 19(3): 631 - 636 - Pubmed link
- Llorente, L. et al., Arthritis Rheum.,2000; 43(8): 1790-800. - Pubmed link
- Lund, S.S. Et al., Eur. J. Endocrinol.,2008;158(5): 631-641. - Pubmed link
- Manneras-Holm, L. et al., J. Clin. Endocrinol. Metab.,2011; 96(4): 1068-1076. - Pubmed link
- Monchanin, G. et al., J Appl Physiol., 2007; 102(1): 169-73. - Pubmed link
- Nebor, D. et al., Haematologica,2011;96(11):1589-1594 - Pubmed link
- Pattan, V.et al., J Clin Med Res,,2015; 7(8): 613-9 - Pubmed link
- Persson, F. et al., Diabetes,2006; 55(12): 3550-5. - Pubmed link
- Persson, F. et al.,Diabetes Care,2009; 32(10): 1873-1879. - Pubmed link
- Sammons J. et al., Stem Cells 2000; 18(3): 214 - 219 - Pubmed link
- Schalkwijk C.G. et al., Ann. N.Y. Acad. Sci, 2005; 1043: 662 - 670 - Pubmed link
- Singh, A. et al., Diabetes Care, 2012; 35: 1322 - 1327 - Pubmed link
- Singhania, N. et al., QJM,2008; 101(6): 449-455. - Pubmed link
- Sotomayor,C.G. et al.,Nutrients. 2017 Jun 2;9(6). pii: E568. - Pubmed link
- Stam, F. et al., Nephrol Dial Transplant,2003; 18(5): 892-8. - Pubmed link
- Tanwar, R. S. et al., Evid Based Complement Alternat Med; 2011: 127641 - Pubmed link
- Unal,D. et al.,Asia Pac Allergy, 2017;7:74-81 - Pubmed link
- Van Dam, B. et al.,Cardiovasc Res.,2003; 57(2): 563-571. - Pubmed link
- Van de Kerkhof J. et al., Nephrol. Dial. Transplant., 2004; 19(4): 910 - 916 - Pubmed link
- van Ree, R. M. et al., Nephrol Dial Transplant,2005; 20(11): 2524-31. - Pubmed link
- Wijnstok, N. J. et al., J Adolesc Health,2010; 47(4): 346-51. - Pubmed link
- Yao, G. H. et al., Lupus,2008;17(8): 720-726. - Pubmed link
- Zedan, M. et al., ISRN Pediatr., 2013: 824781 - Pubmed link
- Ferreira, I. et al.,Diabetologia. 2018 Jan;61(1):231-241. - Pubmed link
- Talasaz, AH. Et al., Iran J Pharm Res. 2018;17(Suppl2) :187-194. - Pubmed link
- Simons, N. et al., Liver Int. 2020 May; 40(5): 1079–1088. - Pubmed link
- Szeremeta, A. et al., J Clin Med. 2022 Jul; 11(14): 4213. - Pubmed link
- Van Damme-Ostapowicz, K. et al., Medicina (Kaunas) 2022 Jan; 58(1): 95. - Pubmed link
BACKGROUND
The vascular cell adhesion protein 1, also known as vascular cell adhesion molecule 1 (VCAM-1) or differentiation group 106 (CD106), is a protein that in humans is coded by the VCAM1 gene. VCAM-1 functions as a cell adhesion molecule.
The VCAM-1 protein induces the adhesion of lymphocytes, monocytes, eosinophils and basophils to the vascular endothelium. It also plays a role in signal transduction of leukocyte-endothelial cells and may play a role in the development of atherosclerosis and rheumatoid arthritis.
Positive regulation of VCAM-1 in endothelial cells by cytokines results from increased transcription of the gene (eg, in response to tumor necrosis factor alpha (TNF-α) and interleukin-1 (IL-1 )) and the stabilization of the messenger RNA. (MRNA) (e.g., interleukin-4 (IL-4)). The promoter region of the VCAM-1 gene contains functional tandem sites NF-KB (nuclear factor-kappa B). The sustained expression of VCAM-1 lasts more than 24 hours.
Mainly, the VCAM-1 protein is an endothelial ligand of the VLA-4 (Very Late Antigen-4 or α4β1 integrin) of the β1 integrin subfamily. VCAM-1 expression has also been observed in other cell types (eg, smooth muscle cells). It has also been shown to interact with EZR and Moesin.
CD106 also exists on the surface of certain sub-populations of mesenchymal stem cells (MSCs).
Version 25 - 09.22
For research use only
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