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Anti-Human IP-10 Azide Free

Product Specifications

Catalogue N°
855.420.000 - 200µg / 200µl
855.420.005 - 500µg / 500µl
Target species
Human
Specificity
Recognises both natural and recombinant IP-10
Clone
B-C55
Application
ELISA
Hybridoma
Myeloma X63/AG.8653 x Balb/c node cells
Immunisation
Recombinant human IP-10
Quantity
200µg or 500µg (Discovery Size also available please enquire)
Isotype
Mouse IgG2a Kappa light chain
Format
Phosphate-buffered saline. Sterile-filtered through 0.22 µm. Carrier and preservative free
Storage
Stable at +2-8°C for 12 months. For longer storage freeze aliquots.
Synonym
CXCL10

BACKGROUND

IP-10 (Interferon-gamma inducible Protein 10kDa) also known as CXCL10, is secreted by several cell types in response to IFNg and LPS. These cell types include monocytes, endothelial cells and fibroblasts.The gene for IP-10 is located on chromosome 4 in a cluster among several other cytokines and encodes a 98 amino acid precursor protein.

Several roles have been attributed to IP-10, such as chemoattraction for monocytes and T cells (but not for neutrophils), inhibition of bone marrow colony formation and angiogenesis, promotion of T cells adhesion molecule expression.

IP-10 shares a common receptor, CXCR3, with the chemokine MIG, but has been shown to play a distinct role in host defense in infections.

IP-10 expression has been associated with HIV infection, is involved in inflammatory skin disease and other allergic diseases; it appears in inflammation of the nervous system and in Alzheimer’s disease (astrocytes expressing IP-10 are commonly associated with senile plaques).

Version 7 - 02.20

For research use only

Documents

For any order, the purchaser acknowledges having read and accepted the terms and conditions described on the Diaclone website.

Formats Available

855.420.000 200µg / 200µl
855.420.005 500µg / 500µl

Ordering options

Place an order
by phone: +33 (0)3 81 41 38 38
or by email: info [at] diaclone [dot] com ( Subject: Diaclone's order, Body: Anti-Human IP-10 Azide Free 855.420.000 - 200µg / 200µl 855.420.005 - 500µg / 500µl )

Please contact us to discuss bulk orders