Search for products

Anti-Human IL-4 PE Conjugated

Product Specifications

Catalogue N°
855.172.010 - 100µg / 1ml
Target species
Human
Specificity
Recognises both natural and recombinant human IL-4
Clone
B-G28
Application
Flow Cytometry
Hybridoma
Myeloma X63/AG.8653 x Balb/c spleen cells
Immunisation
Recombinant human IL-4
Quantity
100 µg / 1ml (Discovery Size also available please enquire)
Isotype
Mouse IgG1 Kappa light chain
Format
Phosphate-buffered saline with 1% BSA and 0,1% sodium azide
Storage
Stable at +2-8°C for six months after reconstitution. DO NOT FREEZE.
Working Dilution
Reconstitute with 1ml of deionized water. It is recommended to establish the optimal dilution according to the system being used. Use 10 μl of antibody to label 5.105 cells

Sodium azide is a poisonous and hazardous substance, handle and dispose of properly


BACKGROUND

IL-4 is a lymphokine that co-stimulates the proliferation of activated B- and T-cells, augments the cytotoxic activity of lymphocytes and monocytes and enhances the functional activity of myeloid cells. Produced by mast cells, T-cells and bone marrow stromal cells, IL-4 regulates the differentiation of naive CD4+ cells into helper Th2 cells characterized by their cytokine secretion-profile that includes secretion of IL-4, IL-5, IL-6, IL-10 and IL-13 which favour a humoral immune response. In addition, IL-4 can inhibit the proliferation of TNF, IL-1 and IL-6 by macrophages.

IL-4 induces B-cell class switching to IgE and IgG1 isotypes, and up regulates MHC Class II production and CD23 expression.

IL-4 is a 15kDa globular glycoprotein containing 129 amino acid residues. The non glycosylated form of the protein is fully biologically active.

Version 8 - 06.19

For research use only

Documents

For any order, the purchaser acknowledges having read and accepted the terms and conditions described on the Diaclone website.

Formats Available

855.172.010 100µg / 1ml

Ordering options

Place an order
by phone: +33 (0)3 81 41 38 38
or by email:

Please contact us to discuss bulk orders