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Anti-Human CD54 Azide Free

Product Specifications

Catalogue N°
853.680.000 - 200µg / 200µl
853.680.005 - 500µg / 500µl
Target species
Human
Specificity
Recognises the Intercellular Adhesion Molecule-1 (ICAM-1), a 75-115 kDa protein
Clone
B-H22
Application
ELISA
Hybridoma
Myeloma X63/AG.8653 x Balb/c spleen cells
Immunisation
Activated human umbilical vein endothelial cells (HUVEC)
Quantity
200µg or 500µg (Discovery Size also available please enquire)
Isotype
Mouse IgG1 Kappa light chain
Format
Phosphate-buffered saline. Sterile-filtered through 0.22 µm. Carrier and preservative free
Storage
Stable at +2-8°C for 12 months. For longer storage freeze aliquots.
Synonym
ICAM-1

BACKGROUND

ICAM-1 (InterCellular Adhesion Molecule) or CD54 is a protein encoded by the human ICAM1 gene located on human chromosome 19. It is present on the surface of endothelial cells and lymphocytes. It can serve as a receptor for viruses of the genus rhinovirus.

The protein encoded by this gene is a type of continuous intercellular adhesion molecule present at low concentrations in leukocyte membranes and endothelial cells. During cytokine stimulation, the concentrations increase considerably. When activated, leukocytes bind to endothelial cells via ICAM-1 / LFA-1 and then transmigrate into tissues.

Version 5 - 06.19

For research use only

Documents

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Formats Available

853.680.000 200µg / 200µl
853.680.005 500µg / 500µl

Ordering options

Place an order
by phone: +33 (0)3 81 41 38 38
or by email:

Please contact us to discuss bulk orders