- Catalogue N°
- 952.691.010 - 100 tests / 1ml
- Target species
- Recognises the Intercellular Adhesion Molecule-1 (ICAM-1), a 75-115 kDa protein
- Flow Cytometry
- Myeloma X63/AG.8653 x Balb/c spleen cells
- Activated human umbilical vein endothelial (HUVEC)
- 100 Tests / 1ml (Discovery Size also available please enquire)
- Mouse IgG1 Kappa light chain
- Phosphate-buffered saline with 1 % BSA and 0.1 % sodium azide
- Stable at +2-8°C for 12 months. For longer storage freeze aliquots.
- Working Dilution
- Use 10 μl to label 106 cells or 100 μl of whole blood
Sodium azide is a poisonous and hazardous substance, handle and dispose of properly
ICAM-1 (InterCellular Adhesion Molecule) or CD54 is a protein encoded by the human ICAM1 gene located on human chromosome 19. It is present on the surface of endothelial cells and lymphocytes. It can serve as a receptor for viruses of the genus rhinovirus.
The protein encoded by this gene is a type of continuous intercellular adhesion molecule present at low concentrations in leukocyte membranes and endothelial cells. During cytokine stimulation, the concentrations increase considerably. When activated, leukocytes bind to endothelial cells via ICAM-1 / LFA-1 and then transmigrate into tissues.
Version 7 - 06.19
For research use only
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