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Human IL-33 ELISA Kit

Product Specifications

Catalogue N°
873.020.048 - 1 x 48 Discovery (pre-coated)
873.020.096 - 1 x 96 (pre-coated)
873.020.192 - 2 x 96 (pre-coated)
Assay Range
31.25 pg/ml - 1000 pg/ml
12.2 pg/ml
Target species
Recognizes both natural and recombinant human IL-33
Sample Type
Serum, Plasma and other body fluids, Cell culture supernatants, Buffered solutions
Sample Size
100 µl (50µl for serum/plasma)
Cross Reaction
No cross reactivity with IL-1b, IL-2, IL-1a, IL-10, IL-12p70, Gp130, IL-17A, IL-23, IFNg, TNFa
Kit Content
Diaclone ELISA Kits include pre-coated strip plates, biotinylated secondary antibody, standards, controls (where applicable), buffers, streptavidin-HRP, TMB, stop reagents and a detailed procedure.
Example of Human IL-33 Standard Curve


Interleukin-33 is described as a IL1 family cytokine which have important functions in host defense, immune regulation and inflammation. It is synthesized as a 30kD precursor ; then cleaved by caspase-1 to generate a 18kD fragment, termed mature IL-33.

IL-33 was originally identified as a protein abundantly expressed in endothelial cells  of high endothelial venules (HEVs) and was previously named NF-HEV (nuclear factor in HEV). High level of IL-33 were also found in fibroblastic reticular cells of lymphoid tissues and certain types of epithelium, including skin keratinocytes and epithelial cells of stomach.

IL-33 induce T helper (Th) type 2 responses by signaling through the IL-1 receptor related protein ST2. Acts as Th2 chemotactic factor,  also promots cytokine production (such as IL-6, IL-13, IL-1b, TNFa), IL-33 has also a role in activating basophil cells and regulating their migration

It is recognized as important contributors to allergic inflammation  by eosinophils cells activation and degranulation.Also contributes to hyperresponsivness reaction observed in asthma when secreted by ephitelial cells.

Version 8 - 09.22

For research use only


For any order, the purchaser acknowledges having read and accepted the terms and conditions described on the Diaclone website.

Formats Available

873.020.048 1 x 48 Discovery (pre-coated)
873.020.096 1 x 96 (pre-coated)
873.020.192 2 x 96 (pre-coated)

Ordering options

Place an order
by phone: +33 (0)3 81 41 38 38
or by email: info [at] diaclone [dot] com ( Subject: Diaclone's order, Body: Human IL-33 ELISA Kit 873.020.048 - 1 x 48 Discovery (pre-coated) 873.020.096 - 1 x 96 (pre-coated) 873.020.192 - 2 x 96 (pre-coated) )

Please contact us to discuss bulk orders