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Human IL-2 ELISpot Pair

Product Specifications

Catalogue N°
869.000.010 - 10 x 96 tests
Target species
Human
Specificity
Recognizes natural human IL-2
Cross Reaction
No cross reactivity with other human cytokines-Cross reactivity with simian IL-2
Kit Content
Diaclone ELISpot matched antibody pairs are extensively validated and include pre-titrated capture antibody and biotinylated detection antibody. Antibodies are supplied in quantities sufficient for 10 x 96 samples.

BACKGROUND

IL-2 is a powerful immunoregulatory lymphokine produced by T-Cells in response to antigenic or mitogenic activation. IL-2 stimulates growth and differentiation of B-Cells, most T-cells, NK cells, monocytes and macrophages .

Mature IL-2 is a 15.4kDa globular glycoprotein containing 133 amino acid residues including one intrachain disulfide bond between residues 58 and 105.

Apart from its most important role to mediate antigen-specific T-lymphocyte proliferation, IL-2 modulates the expression of interferon-g and major histocompatibility antigens.

Alterations in the ability of T-cell  to synthesize IL-2 have been observed in physiologic and pathologic states. Currently, IL-2 is used to enhance the immune system of patients for the treatment of cancer and infectious disease.

Version 4 - 07.19

For research use only

Documents

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Formats Available

869.000.010 10 x 96 tests

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