Murine IL-2 ELISpot Kit

Product Specifications

Catalogue N°

862.001.001PC - 1 x 96 Discovery (pre-coated plate)
862.001.002PC - 2 x 96 (pre-coated plates)
862.001.005PC - 5 x 96 (pre-coated plates)

Target species

Murine

Specificity

Recognizes natural murine IL-2

Incubation

3h after cell stimulation

Cross Reaction

No cross reactivity with other murine cytokines

Kit Content

Diaclone Pre-coated ELISpot kits include precoated PVDF plates, Detection antibody, Alkaline phosphatase conjugate, BSA, BCIP/NBT ready-to-use substrate buffer.

• References
• Related products

BACKGROUND

IL-2 is a powerful immunoregulatory lymphokine produced by T-Cells in response to antigenic or mitogenic activation. IL-2 stimulates growth and differentiation of B-Cells, most T-cells, NK cells, monocytes and macrophages.

Mature IL-2 is a 15.4kDa globular glycoprotein containing 133 amino acid residues including one intrachain disulfide bond between residues 58 and 105.

Apart from its most important role to mediate antigen-specific T-lymphocyte proliferation, IL-2 modulates the expression of interferon-g and major histocompatibility antigens.

Alterations in the ability of T-cell to synthesize IL-2 have been observed in physiologic and pathologic states. Currently, IL-2 is used to enhance the immune system of patients for the treatment of cancer and infectious disease.

Version 6 - 01.21

For research use only

For any order, the purchaser acknowledges having read and accepted the terms and conditions described on the Diaclone website.