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Anti-Human IL-17F Unconjugated

Product Specifications

Catalogue N°
855.563.020 - 200 tests / 2ml
Target species
Human
Specificity
Recognises both natural and recombinant human IL-17F
Clone
B-C52
Application
Flow Cytometry
Hybridoma
Myeloma X63/AG.8653 x Balb/c node cells
Immunisation
Recombinant human IL-17F
Quantity
200 Tests / 2ml (Discovery Size also available please enquire)
Isotype
Mouse IgG1 Kappa light chain
Format
Phosphate-buffered saline with 1% BSA and 0.09% sodium azide
Storage
Stable at +2-8°C for 12 months. For longer storage freeze aliquots.
Working Dilution
Use 10 μl to label 106 cells or 100 μl of whole blood
Anti-Human IL-17F Unconjugated
The graph on the right represents activated TH17 cells (5h by PMA-ionomycin) marked with B-C52 and the graph on the left shows B-C52 with non-activated TH17 cells.
In both cases, the dotted line represents the IgG1 isotype control (B-Z1)

Sodium azide is a poisonous and hazardous substance, handle and dispose of properly


BACKGROUND

IL-17F,discovered in 2001, is a member of the IL-17 family of cytokines produced by activated T-cells CD4+ and monocytes. IL-17F has been considered as an inflammatory cytokine since it induces many proinflammatory cytokines and chemokines. IL-17F shares strongest homology to IL-17A (sharing about 50% amino acid). The IL-17A and IL-17F genes are localized in the same chromosome region. An IL-17A/F heterodimer biologically active was found to be expressed in Th17 cells together with IL-17A and IL-17F homodimers.

Version 4 - 06.19

For research use only

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Formats Available

855.563.020 200 tests / 2ml

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