Anti-Human IL-27 Azide Free

Product Specifications

Catalogue N°

855.300.000 - 200µg / 200µl
855.300.005 - 500µg / 500µl

Target species

Human

Specificity

Recognises both natural and recombinant human IL-27

Clone

B-G49

Application

ELISA

Flow Cytometry

Hybridoma

Myeloma X63/AG.8653 x Balb/c node cells

Immunisation

Recombinant human IL-27

Quantity

200µg or 500µg (Discovery Size also available please enquire)

Isotype

Mouse IgG2a Kappa light chain

Format

Phosphate-buffered saline. Sterile-filtered through 0.22 µm. Carrier and preservative free

Storage

Stable at +2-8°C for 12 months. For longer storage freeze aliquots.

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BACKGROUND

Interleukin IL-27 (IL-27) is a heterodimeric cytokine belonging to the IL-12 family that is composed of two subunits,Epstein-Barr virus-induced gene 3 (EBI3), a 33-kDa glycosylated protein, and IL-27p28, a 28-kDa peptide. IL-27 is an early product of activated antigen-presenting cells and drives rapid clonal expansion of naïve but not memory CD4+ T cells. The effects of IL-27 are eliciting by its interaction with a specific cell surface receptor complex composed of two proteins known as WSX-1 (TCCR) and gp130. IL-27 has both pro- and anti-inflammatory properties.

Version 7 - 06.19

For research use only

Documents

• Safety Data Sheet Mab Azide Free

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