Anti-Human CD54 Azide Free

Product Specifications

Catalogue N°

853.680.000 - 200µg / 200µl
853.680.005 - 500µg / 500µl

Target species

Human

Specificity

Recognises the Intercellular Adhesion Molecule-1 (ICAM-1), a 75-115 kDa protein

Clone

B-H22

Application

ELISA

Hybridoma

Myeloma X63/AG.8653 x Balb/c spleen cells

Immunisation

Activated human umbilical vein endothelial cells (HUVEC)

Quantity

200µg or 500µg (Discovery Size also available please enquire)

Isotype

Mouse IgG1 Kappa light chain

Format

Phosphate-buffered saline. Sterile-filtered through 0.22 µm. Carrier and preservative free

Storage

Stable at +2-8°C for 12 months. For longer storage freeze aliquots.

Synonym

ICAM-1

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BACKGROUND

ICAM-1 (InterCellular Adhesion Molecule) or CD54 is a protein encoded by the human ICAM1 gene located on human chromosome 19. It is present on the surface of endothelial cells and lymphocytes. It can serve as a receptor for viruses of the genus rhinovirus.

The protein encoded by this gene is a type of continuous intercellular adhesion molecule present at low concentrations in leukocyte membranes and endothelial cells. During cytokine stimulation, the concentrations increase considerably. When activated, leukocytes bind to endothelial cells via ICAM-1 / LFA-1 and then transmigrate into tissues.

Version 5 - 06.19

For research use only

Documents

• Safety Data Sheet Mab Azide Free

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