Anti-Human CD50 Unconjugated

Product Specifications

Catalogue N°

852.673.020 - 200 tests / 2ml

Target species

Human

Specificity

Recognises the Intercellular Adhesion Molecule-3 (ICAM-3), a 110-140 kDa protein

Clone

B-R1

Application

Flow Cytometry

Immuno-Precipitation

Hybridoma

Myeloma X63/AG.8653 x Balb/c spleen cells

Immunisation

U266 cell line

Quantity

200 Tests / 2ml (Discovery Size also available please enquire)

Isotype

Mouse IgG1 Kappa light chain

Format

Phosphate-buffered saline with 1% BSA and 0.09% sodium azide

Workshop

VI

Storage

Stable at +2-8°C for 12 months. For longer storage freeze aliquots.

Working Dilution

Use 10 μl to label 10⁶ cells or 100 μl of whole blood

Synonym

ICAM-3

• References
• Related products

Sodium azide is a poisonous and hazardous substance, handle and dispose of properly

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BACKGROUND

The intercellular adhesion molecule 3 (ICAM 3), also called CD50 (Cluster of Differentiation 50), is a protein which, in humans, is encoded by the ICAM 3 gene.

The protein encoded by this gene belongs to the family of intercellular adhesion molecules (ICAM). All ICAM proteins are type I transmembrane glycoproteins, contain 2 to 9 immunoglobulin type C2 domains, and bind to LFA-1 leukocyte adhesion protein. This protein is constitutively and abundantly expressed by all leukocytes and may be the most important ligand for LFA-1 in initiating the immune response.  It functions not only as an adhesion molecule, but also as a powerful signaling molecule.

Version 5 - 06.19

For research use only

Documents

• Safety Data Sheet Mab Purified

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