Human IL-17A ELISA Set

Product Specifications

Catalogue N°

851.720.001 - 1 x 96 Discovery
851.720.005 - 5 x 96
851.720.010 - 10 x 96
851.720.015 - 15 x 96
851.720.020 - 20 x 96

Assay Range

3.12 pg/ml - 100 pg/ml

Sensitivity

3 pg/ml

Target species

Human

Specificity

Recognizes both natural and recombinant human IL-17A

Incubation

From sample to end 3h45

Sample Type

Serum, Plasma, Cell culture supernatant

Sample Size

100 µl

Cross Reaction

No cross reactivity with other human cytokines

Kit Content

Diaclone ELISA Sets include capture and biotinylated detection antibody, one standard per plate, Streptavidin-HRP, TMB, and detailed procedure including buffer composition.

• References
• Related products

BACKGROUND

Interleukin-17 (IL-17, or IL-17A) is the founding member of a group of cytokines called the IL-17 family. IL-17A, was originally identified as a transcript from a rodent T-cell hybridoma by Rouvier et al. in 1993.

IL-17A is involved in inducing and mediating proinflammatory responses, commonly associated with allergic responses and induces the production of many other cytokines (such as IL-6, G-CSF, GM-CSF, IL-1β, TGF-β, TNF-α), chemokines (including IL-8, GRO-α and MCP-1) and prostaglandins (e.g. PGE2) from many cell types (fibroblasts, endothelial cells, epithelial cells, keratinocytes and macrophages).

IL-17A function is also essential to a subset of CD4+ T-Cells called T helper 17 (Th17) cells.

Version 6 - 07.19

For research use only

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