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Human IL-17A ELISA Set

Product Specifications

Catalogue N°
851.720.001 - 1 x 96 Discovery
851.720.005 - 5 x 96
851.720.010 - 10 x 96
851.720.015 - 15 x 96
851.720.020 - 20 x 96
Assay Range
3.12 pg/ml - 100 pg/ml
Sensitivity
3 pg/ml
Target species
Human
Specificity
Recognizes both natural and recombinant human IL-17A
Incubation
From sample to end 3h45
Sample Type
Serum, Plasma, Cell culture supernatant
Sample Size
100 µl
Cross Reaction
No cross reactivity with other human cytokines
Kit Content
Diaclone ELISA Sets include capture and biotinylated detection antibody, one standard per plate, Streptavidin-HRP, TMB, and detailed procedure including buffer composition.

BACKGROUND

Interleukin-17 (IL-17, or IL-17A) is the founding member of a group of cytokines called the IL-17 family. IL-17A, was originally identified as a transcript from a rodent T-cell hybridoma by Rouvier et al. in 1993.

IL-17A is involved in inducing and mediating proinflammatory responses, commonly associated with allergic responses and induces the production of many other cytokines (such as IL-6, G-CSF, GM-CSF, IL-1β, TGF-β, TNF-α), chemokines (including IL-8, GRO-α and MCP-1) and prostaglandins (e.g. PGE2) from many cell types (fibroblasts, endothelial cells, epithelial cells, keratinocytes and macrophages).

IL-17A function is also essential to a subset of CD4+ T-Cells called T helper 17 (Th17) cells.

Version 6 - 07.19

For research use only

Documents

For any order, the purchaser acknowledges having read and accepted the terms and conditions described on the Diaclone website.

Formats Available

851.720.001 1 x 96 Discovery
851.720.005 5 x 96
851.720.010 10 x 96
851.720.015 15 x 96
851.720.020 20 x 96

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