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Human IL-23 ELISA Kit

Product Specifications

Catalogue N°
850.920.048 - 1 x 48 Discovery (pre-coated)
850.920.096 - 1 x 96 (pre-coated)
850.920.192 - 2 x 96 (pre-coated)
Assay Range
156.25 pg/ml - 5000 pg/ml
Sensitivity
20 pg/ml
Target species
Human
Specificity
Recognizes both natural and recombinant human IL-23
Incubation
2h45
Sample Type
Serum, Plasma, Cell culture supernatant
Sample Size
100 µl
Kit Content
Diaclone ELISA Kits include pre-coated strip plates, biotinylated secondary antibody, standards, controls (where applicable), buffers, streptavidin-HRP, TMB, stop reagents and a detailed procedure.
IL-23 ELISA Kit
Example of Human IL-23 Standard Curve

References

  • Bellanger, A.-P. et al.,Clin. Vaccine Immunol., 2013 ; 20(8): 1133-1142. - Pubmed link
  • Darmochwal-Kolarz, D. et al.,Biomed Res Int. 2017;2017:6904325. - Pubmed link
  • Esfahanian, F. et al.,Indian J Endocrinol Metab. 2017 Jul-Aug;21(4):551-554 - Pubmed link
  • Madej, M. et al., Reumatologia,2015; 53(1): 9-13. - Pubmed link
  • Rana, A. et al.,Lupus,2012; 21(10): 1105-1112 - Pubmed link
  • Szpakowski, P. et al., J Immunol Res.,2015; 2015: 359153 - Pubmed link
  • Wlodarczyk, M. et al.,World J Gastroenterol.,2014;20(22):7019-26 - Pubmed link
  • Sugiura, T. et al., J Immunol. 2020 Dec 15; 205(12): 3277–3290. - Pubmed link
  • Velikova, T. V. et al., World J Gastroenterol. 2020 Apr 28; 26(16): 1912–1925. - Pubmed link
  • Jaszczura, M. et al., Rheumatol Int. 2019; 39(11): 1945–1953. - Pubmed link
  • Divyapriya, D. et al., Postepy Dermatol Alergol. 2021 Oct; 38(5): 858–865. - Pubmed link
  • Kowalewicz-Kulbat, M. et al., Vaccines (Basel) 2021 Mar; 9(3): 277. - Pubmed link

BACKGROUND

Interleukin-23 is a heterodimeric cytokine consisting in two subunits : p40, shared  with IL-12 and a distinct one p19 (the IL-23  subunit). Although IL-12 activates naive T cells, the initial description of IL-23 was the preferential action on memory T cells to increase IFNg production. In conjonction with IL-6 and TGF-b1, IL-23 is necessary to maintain the Th1 lineage. IL-23 plays an important role in the inflammatory response against infection, and is implicated in the developpement of cancerous tumors and auto immune diseases. Over expression of p19 correlates with inflammation in multiple organs and epithelial tissues including skin.

Version 14 - 02.22

For research use only

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Formats Available

850.920.048 1 x 48 Discovery (pre-coated)
850.920.096 1 x 96 (pre-coated)
850.920.192 2 x 96 (pre-coated)

Ordering options

Place an order
by phone: +33 (0)3 81 41 38 38
or by email: info [at] diaclone [dot] com ( Subject: Diaclone's order, Body: Human IL-23 ELISA Kit 850.920.048 - 1 x 48 Discovery (pre-coated) 850.920.096 - 1 x 96 (pre-coated) 850.920.192 - 2 x 96 (pre-coated) )

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