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Human IL-4 High Sensitivity ELISA Kit

Product Specifications

Catalogue N°
850.890.048 - 1 x 48 Discovery (pre-coated)
850.890.096 - 1 x 96 (pre-coated)
850.890.192 - 2 x 96 (pre-coated)
Assay Range
0.31 pg/ml - 10 pg/ml
Sensitivity
0.31 pg/ml
Target species
Human
Specificity
Recognizes both natural and recombinant human IL-4
Incubation
4h00
Sample Type
Serum, Plasma, Cell culture supernatant
Sample Size
100 µl
Cross Reaction
No cross reactivity with other human cytokines
Kit Content
Diaclone High Sensitivity ELISA Kits include pre-coated strip plates, biotinylated secondary antibody, standards, controls (where applicable), buffers, streptavidin-HRP, TMB, stop reagents and a detailed procedure.
IL-4 HS ELISA Kit
IL-4 HS ELISA Kit

BACKGROUND

IL-4 is a lymphokine that co-stimulates the proliferation of activated B- and T-cells, augments the cytotoxic activity of lymphocytes and monocytes and enhances the functional activity of myeloid cells . Produced by mast cells, T-cells and bone marrow stromal cells, IL-4 regulates the differentiation of naive CD4+ cells into helper Th2 cells characterized by their cytokine secretion-profile that includes secretion of IL-4, IL-5, IL-6, IL-10 and IL-13 which favour a humoral immune response. In addition, IL-4 can inhibit the proliferation of TNF, IL-1 and IL-6 by macrophages.

IL-4 induces B-cell class switching to IgE and IgG1 isotypes, and up regulates MHC Class II production and CD23 expression.

IL-4 is a 15kDa globular glycoprotein containing 129 amino acid residues. The non-glycosylated form of the protein is fully biologically active.

Version 5 - 04.20

For research use only

Documents

For any order, the purchaser acknowledges having read and accepted the terms and conditions described on the Diaclone website.

Formats Available

850.890.048 1 x 48 Discovery (pre-coated)
850.890.096 1 x 96 (pre-coated)
850.890.192 2 x 96 (pre-coated)

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