Human IL-2 High Sensitivity ELISA Kit

Product Specifications

Catalogue N°

850.870.048 - 1 x 48 Discovery (pre-coated)
850.870.096 - 1 x 96 (pre-coated)
850.870.192 - 2 x 96 (pre-coated)

Assay Range

1.87 pg/ml - 60 pg/ml

Sensitivity

0.97 pg/ml

Target species

Human

Specificity

Recognizes both natural and recombinant human IL-2

Incubation

2h00

Sample Type

Serum, Plasma, Cell culture supernatant

Sample Size

100 µl

Cross Reaction

No cross reactivity with other human cytokines

Kit Content

Diaclone High Sensitivity ELISA Kits include pre-coated strip plates, biotinylated secondary antibody, standards, controls (where applicable), buffers, streptavidin-HRP, TMB, stop reagents and a detailed procedure.

• References
• Related products

BACKGROUND

IL-2 is a powerful immunoregulatory lymphokine produced by T-Cells in response to antigenic or mitogenic activation. IL-2 stimulates growth and differentiation of B-Cells, most T-cells, NK cells, monocytes and macrophages.

Mature IL-2 is a 15.4kDa globular glycoprotein containing 133 amino acid residues including one intrachain disulfide bond between residues 58 and 105.

Apart from its most important role to mediate antigen-specific T-lymphocyte proliferation, IL-2 modulates the expression of interferon-g and major histocompatibility antigens.

Alterations in the ability of T-cell to synthesize IL-2 have been observed in physiologic and pathologic states. Currently, IL-2 is used to enhance the immune system of patients for the treatment of cancer and infectious disease.

Version 6 - 09.22

For research use only

For any order, the purchaser acknowledges having read and accepted the terms and conditions described on the Diaclone website.