Human IL-17A ELISA Kit
Product Specifications
- Catalogue N°
- 850.940.048 - 1 x 48 Discovery (pre-coated)
850.940.096 - 1 x 96 (pre-coated)
850.940.192 - 2 x 96 (pre-coated) - Assay Range
- 3.125 pg/ml - 1000 pg/ml
- Sensitivity
- 2.3 pg/ml
- Target species
- Human
- Specificity
- Recognizes both natural and recombinant human IL-17A
- Incubation
- 3h45
- Sample Type
- Serum, Plasma, Cell culture supernatant
- Sample Size
- 100 µl (50µl for serum/plasma)
- Cross Reaction
- No cross reaction with other human cytokines
- Kit Content
- Diaclone ELISA Kits include pre-coated strip plates, biotinylated secondary antibody, standards, controls (where applicable), buffers, streptavidin-HRP, TMB, stop reagents and a detailed procedure.
References
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BACKGROUND
Interleukin-17 (IL-17, or IL-17A) is the founding member of a group of cytokines called the IL-17 family. IL-17A, was originally identified as a transcript from a rodent T-cell hybridoma by Rouvier et al. in 1993.
IL-17A is involved in inducing and mediating proinflammatory responses, commonly associated with allergic responses and induces the production of many other cytokines (such as IL-6, G-CSF, GM-CSF, IL-1β, TGF-β, TNF-α), chemokines (including IL-8, GRO-α and MCP-1) and prostaglandins (e.g. PGE2) from many cell types (fibroblasts, endothelial cells, epithelial cells, keratinocytes and macrophages).
IL-17A function is also essential to a subset of CD4+ T-Cells called T helper 17 (Th17) cells.
Version 17 - 09.22
For research use only
For any order, the purchaser acknowledges having read and accepted the terms and conditions described on the Diaclone website.