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Murine IP-10 ELISA kit

Product Specifications

Catalogue N°
660.120.096 - 1 x 96 (pre-coated)
660.120.192 - 2 x 96 (pre-coated)
Assay Range
7.8 pg/ml - 500 pg/ml
Sensitivity
6.5pg/ml
Target species
Murine
Specificity
Recognizes both natural and recombinant murine IP-10
Incubation
3h10
Sample Type
Cell culture supernatant and serum tested, other body fluids suitable
Sample Size
50 µl
Kit Content
Diaclone ELISA Kits include pre-coated strip plates, biotinylated secondary antibody, standards, controls (where applicable), buffers, streptavidin-HRP, TMB, stop reagents and a detailed procedure.
Synonym
CXCL10
mIP-10 ELISA Kit
mIP-10 ELISA Kit

BACKGROUND

IP-10 is a member of the CXC subfamily of chemokines expressed by monocytes. It plays a pivotal role in immune system development and deployment. The Interferon-gamma inducible protein -10kD (IP-10) displays pleiotropic functions including stimulation of monocytes, natural killer and T-cell migration, regulation of T-cell and bone marrow progenitor maturation, modulation of adhesion molecule expression as well as inhibition of angiogenesis.

Through this inhibitory effect on neovascularization IP-10 exhibits anti-tumoral effects. It shares a common receptor, CXCR3, with the chemokine MIG, but has been shown to play a distinct role in host defense in infections. IP-10 is further involved in allergic contact dermatitis reactions and other allergic diseases. It appears during immune-mediated processes, in inflammation of the nervous system and in Alzheimer’s disease.

Its involvement in the regulation of fibroproliferation following inflammatory lung injury has been described.

Version 3 - 07.19

For research use only

Documents

For any order, the purchaser acknowledges having read and accepted the terms and conditions described on the Diaclone website.

Formats Available

660.120.096 1 x 96 (pre-coated)
660.120.192 2 x 96 (pre-coated)

Ordering options

Place an order
by phone: +33 (0)3 81 41 38 38
or by email: info [at] diaclone [dot] com ( Subject: Diaclone's order, Body: Murine IP-10 ELISA kit 660.120.096 - 1 x 96 (pre-coated) 660.120.192 - 2 x 96 (pre-coated) )

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