Human IL-27 ELISA Kit

Product Specifications

Catalogue N°

850.960.048 - 1 x 48 Discovery (pre-coated)
850.960.096 - 1 x 96 (pre-coated)
850.960.192 - 2 x 96 (pre-coated)

Assay Range

31.25 pg/ml - 1000 pg/ml

Sensitivity

12.8 pg/ml

Target species

Human

Specificity

Recognizes both natural and recombinant human IL-27

Incubation

3h45

Sample Type

Serum, Plasma, Cell culture supernatant

Sample Size

100 µl

Cross Reaction

No cross reactivity with other human cytokines

Kit Content

Diaclone ELISA Kits include pre-coated strip plates, biotinylated secondary antibody, standards, controls (where applicable), buffers, streptavidin-HRP, TMB, stop reagents and a detailed procedure.

• References
• Related products

BACKGROUND

Interleukin IL-27 (IL-27) is a heterodimeric cytokine belonging to the IL-12 family that is composed of two subunits,Epstein-Barr virus-induced gene 3 (EBI3), a 33-kDa glycosylated protein, and IL-27p28, a 28-kDa peptide. IL-27 is an early product of activated antigen-presenting cells and drives rapid clonal expansion of naïve but not memory CD4+ T cells. The effects of IL-27 are eliciting by its interaction with a specific cell surface receptor complex composed of two proteins known as WSX-1 (TCCR) and gp130. IL-27 has both pro- and anti-inflammatory properties.

Version 7 - 11.21

For research use only

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