Anti-Human CD54 Unconjugated

Product Specifications

Catalogue N°

852.693.020 - 200 tests / 2ml

Target species

Human

Specificity

Recognises the Intercellular Adhesion Molecule-1 (ICAM-1), a 75-115 kDa protein

Clone

B-H17

Application

Flow Cytometry

Immuno-Precipitation

Hybridoma

Myeloma X63/AG.8653 x Balb/c spleen cells

Immunisation

Activated human umbilical vein endothelial (HUVEC)

Quantity

200 Tests / 2ml (Discovery Size also available please enquire)

Isotype

Mouse IgG1 Kappa light chain

Format

Phosphate-buffered saline with 1% BSA and 0.09% sodium azide

Workshop

VI

Storage

Stable at +2-8°C for 12 months. For longer storage freeze aliquots.

Working Dilution

Use 10 μl to label 10⁶ cells or 100 μl of whole blood

Synonym

ICAM-1

• References
• Related products

Sodium azide is a poisonous and hazardous substance, handle and dispose of properly

BACKGROUND

ICAM-1 (InterCellular Adhesion Molecule) or CD54 is a protein encoded by the human ICAM1 gene located on human chromosome 19. It is present on the surface of endothelial cells and lymphocytes. It can serve as a receptor for viruses of the genus rhinovirus.

The protein encoded by this gene is a type of continuous intercellular adhesion molecule present at low concentrations in leukocyte membranes and endothelial cells. During cytokine stimulation, the concentrations increase considerably. When activated, leukocytes bind to endothelial cells via ICAM-1 / LFA-1 and then transmigrate into tissues.

Version 7 - 06.19

For research use only

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