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Anti-Human CD126 Azide Free

Formats Available:

(852.030.000) 200µg / 200µl Azide free

 

Product Specifications

 

CATALOGUE N° :     852.030.000
CLONE :     B-R6
ISOTYPE :     Mouse IgG1
IMMUNISATION :     gp80 transfected CHO cell line
HYBRIDOMA :     Myeloma X63/AG.8653 x Balb/c spleen cells
SPECIFICITY :     Recognises the Interleukin-6 Rα subunit, IL-6 Ra, IL-6 R, a 80 kDa protein
WORKSHOP :     V - VI
QUANTITY :     200 µg / 200 µl (Discovery Size also available please enquire)
FORMAT :     Phosphate-buffered saline. Sterile-filtered through 0.22 µm and treated to remove endotoxins. Carrier and preservative free
STORAGE :     Stable at +2-8°C for 12 months
For longer storage, freeze aliquots
APPLICATION :     Suitable for flow cytometry
Blocks IL-6 induced proliferation of XG-1 cells
Inhibits IL-6 binding to its receptor
Suitable for immunoprecipitation and immunohistochemistry on frozen sections
Western Blot : not tested
Recognises soluble and membrane bound IL-6 R
OTHER :     Kd : 1.22 nM
REFERENCES :    
Burger R. et al., The Haematology Journal, 2001; 2: 42-53
Burger, R. et al.,Haematologica, 2017;102(2) :381-390
Clement C. et al, CR.3.2 Leucocyte Typing V, Boston, 1993
Dubois B. et al., J. Immunol., 1998; 161 : 2223 -2231  
Dubois B. et al., J. Immunol., 1999; 162 : 3428 -3436  
Gougelet, A. et al.,PLoS One,2009;4(11):e8026   
Gu, Z. J. et al., Leukemia,2000; 14(1): 188-97.  
Menetrier-Caux C. et al., Blood, 1998; 92 : 4778 - 4791
Muller-Newen, G. et al., Eur J Biochem.,1996; 236(3): 837-42.

                            graph
A typical staining pattern with the B-R6 monoclonal antibody of U266 cell line
Version 7 - 12.16                                       For research use only