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Anti-Human IL-2 Azide Free

Product Specifications

Catalogue N°
855.020.000 - 200µg / 200µl
855.020.005 - 500µg / 500µl
Target species
Human
Specificity
Recognises both natural and recombinant human IL-2
Clone
B-G5
Application
ELISA
Flow Cytometry
Functional assay
Western Blot
ELISpot
Hybridoma
Myeloma X63/AG.8653 x Balb/c spleen cells
Immunisation
Natural human IL-2
Quantity
200µg or 500µg (Discovery Size also available please enquire)
Isotype
Mouse IgG1 Kappa light chain
Format
Phosphate-buffered saline. Sterile-filtered through 0.22 μm. Carrier and preservative free
Storage
Store at +2-8°C for 12 months. DO NOT FREEZE.
Biological Activity
Inhibits IL-2 induced proliferation on Kit 225 cell line
Anti-Human IL-2 Azide Free
The graph on the left represents activated lymphocytes marked with B-G5.
Anti-Human IL-2 Azide Free
The graph on the right shows B-G5 with non-activated lymphocytes. In the two cases, the dotted line represents the IgG1 isotype control.

BACKGROUND

IL-2 is a powerful immunoregulatory lymphokine produced by T-Cells in response to antigenic or mitogenic activation.IL-2 stimulates growth and differentiation of B-Cells, most T-cells, NK cells, monocytes and macrophages.

Mature IL-2 is a 15.4kDa globular glycoprotein containing 133 amino acid residues including one intrachain disulfide bond between residues 58 and 105.

Apart from its most important role to mediate antigen-specific T-lymphocyte proliferation, IL-2 modulates the expression of interferon-g and major histocompatibility antigens.

Alterations in the ability of T-cell to synthesize IL-2 have been observed in physiologic and pathologic states. Currently, IL-2 is used to enhance the immune system of patients for the treatment of cancer and infectious disease.

Version 15 - 05.21

For research use only

Documents

For any order, the purchaser acknowledges having read and accepted the terms and conditions described on the Diaclone website.

Formats Available

855.020.000 200µg / 200µl
855.020.005 500µg / 500µl

Ordering options

Place an order
by phone: +33 (0)3 81 41 38 38
or by email: info [at] diaclone [dot] com ( Subject: Diaclone's order, Body: Anti-Human IL-2 Azide Free 855.020.000 - 200µg / 200µl 855.020.005 - 500µg / 500µl )

Please contact us to discuss bulk orders