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Anti-Human CD130 Azide Free

Formats Available:

(852.060.000) 200µg / 200µl Azide free

 

Product Specifications

 

CATALOGUE N° :     852.060.000
CLONE :     B-R3
ISOTYPE :     Mouse IgG2a
IMMUNISATION :     Natural soluble gp130
HYBRIDOMA :     Myeloma X63/AG.8653 x Balb/c spleen cells
SPECIFICITY :     Recognises the Gp130, common subunit for IL-6, IL-11, OSM, LIF, CNTF, CT-1 receptors, a 130-140 kDa protein
WORKSHOP :     VI
QUANTITY :     200 µg / 200 µl (Discovery Size also available please enquire)
FORMAT :     Phosphate-buffered saline. Sterile-filtered through 0.22 µm and treated to remove endotoxins. Carrier and preservative free
STORAGE :     Stable at +2-8°C for 12 months
For longer storage, freeze aliquots
APPLICATION :     Suitable for flow cytometry
Inhibits IL-6, IL-11, CNTF, LIF and OSM activities
Inhibits OSM and CNTF binding to gp130
Immunohistochemistry : not tested
Recognises the soluble antigen
REFERENCES :    
Aoki, Y. et al., Blood,2001; 98(10): 3042-9.
Auguste, P. et al., J Biol Chem.,1997; 272(25): 15760-4.
Blanchard M. et al., J. Biol. Chem., 1998; 273(33): 20886 -20893
Burger R. et al., The Haematology Journal, 2001; 2(1): 42-53
Burger, R. et al.,Haematologica, 2017;102(2) :381-390
Chautard, E. et al.,Neuro Oncology,2010;12(5): 434-443
Chevalier S. et al., J. Biol. Chem., 1996; 271(25): 14764-72
Duplomb L. et al., Endocrinology, 2003; 144(12) : 5381 - 5389
Gougelet, A. et al.,PLoS One,2009; 4(11): e8026
Gu, Z. J. et al., Blood,1996; 88(10): 3972-86.
Gu, Z. J. et al., Leukemia,2000; 14(1): 188-97.
Gu, Z. J. et al., J Immunol Methods,1996; 190(1): 21-7.
Jover, R. et al., Faseb J.,2002; 16(13): 1799-801.
Kube D. et al., Blood, 2001; 98(3) : 762 - 770
Lebeau, B. et al., FEBS Lett.,1997; 407(2): 141-7
Leslie, K. et al., Breast Cancer Res.,2010; 12(5): R80.
Magrangeas, F. et al. ,Biochem J.,2001; 353(Pt 2): 223-30.
Memoli, B., Nephrol. Dial. Transplant,2001; 16(6): A184-186.
Memoli, B. et al., J Am Soc Nephrol.,2005; 16(4): 1099-107.
Müller-Newen G. et al., J. Biol. Chem., 2000; 275 (7) : 4578 - 4586
Olivier, C. et al., J Biol Chem.,2000; 275(8): 5648-56.
Taupin J-L. et al., J. Biol. Chem., 2001; 276(51) : 47975 - 47981
Thiel, S. et al., Biochem.,1998; J 330 (Pt 1): 47-54.
Waetzig, G. H. et al.,J. Biol. Chem.,2010; 285(3):1781-1789

                          graph
A typical staining pattern with the B-R3 monoclonal antibody of Eahy 926 cell line
Version 9 - 06.17                                           For research use only